Manforce is a prescription medication containing sildenafil citrate, a phosphodiesterase type 5 (PDE5) inhibitor, designed for the effective management of erectile dysfunction (ED). It functions by enhancing blood flow to the penile tissues during sexual stimulation, facilitating the achievement and maintenance of an erection sufficient for satisfactory sexual activity. This medication is intended for adult males and requires appropriate medical evaluation prior to initiation to ensure suitability and safety. Proper understanding of its pharmacological profile, administration guidelines, and potential risks is essential for optimal therapeutic outcomes and patient safety.

Features

• Active ingredient: Sildenafil citrate 25mg, 50mg, or 100mg per tablet
• Rapid onset of action, typically within 30–60 minutes post-administration
• Duration of efficacy up to 4–6 hours
• Film-coated tablet for ease of swallowing
• Requires sexual stimulation for effect
• Prescription-only status ensuring supervised use

Benefits

• Significantly improves the ability to achieve and sustain an erection
• Enhances sexual confidence and reduces performance-related anxiety
• Supports intimate relationship satisfaction through reliable efficacy
• Allows for spontaneity with a sufficiently long window of effectiveness
• Backed by extensive clinical research and safety data
• Available in multiple dosages for individualized treatment plans

Common use

Manforce is indicated for the treatment of erectile dysfunction in adult males. It is used on an as-needed basis prior to anticipated sexual activity. It is not intended for use by women, adolescents, or individuals without a clinical diagnosis of ED. The medication should only be used under the guidance of a healthcare provider following a comprehensive medical assessment to identify underlying causes of erectile dysfunction.

Dosage and direction

The recommended starting dose is 50 mg taken approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to a maximum of 100 mg or decreased to 25 mg. Do not exceed one dose within a 24-hour period. The tablet should be swallowed whole with a glass of water; it may be taken with or without food, though high-fat meals may delay onset of action. Sexual stimulation is required for the medication to be effective.

Precautions

• Not for use in individuals with cardiovascular conditions where sexual activity is inadvisable
• Avoid consumption of grapefruit or grapefruit juice, as it may increase sildenafil concentrations
• Use with caution in patients with anatomical penile deformities or conditions predisposing to priapism
• May cause hypotension; caution advised in patients on antihypertensive therapy
• Not recommended for use with other ED treatments or recreational drugs
• Contains lactose; not suitable for patients with galactose intolerance or Lapp lactase deficiency

Contraindications

• Concomitant use of organic nitrates or nitric oxide donors in any form
• History of hypersensitivity to sildenafil or any excipients in the formulation
• Severe hepatic impairment
• Severe hypotension or uncontrolled hypertension
• Recent history of stroke, myocardial infarction, or life-threatening arrhythmia
• Hereditary degenerative retinal disorders

Possible side effects

Common side effects may include headache, flushing, dyspepsia, nasal congestion, dizziness, and visual disturbances (such as altered color perception). Less frequently reported effects include myalgia, back pain, and nausea. Priapism (prolonged and painful erection lasting more than 4 hours) is a rare but serious adverse event requiring immediate medical attention to prevent permanent tissue damage.

Drug interaction

Sildenafil is primarily metabolized by CYP3A4 and may interact with:

• Nitrates (e.g., nitroglycerin, isosorbide mononitrate) — contraindicated
• Alpha-blockers (e.g., doxazosin) — increased risk of hypotension
• CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, erythromycin) — may increase sildenafil exposure
• CYP3A4 inducers (e.g., rifampicin) — may reduce efficacy
• Antihypertensive agents — additive hypotensive effects

Missed dose

Manforce is not intended for regular daily dosing. If a dose is missed, it may be taken when remembered, provided it is at least 24 hours before the next anticipated sexual activity. Do not double the dose to make up for a missed one.

Overdose

In case of suspected overdose, seek immediate medical attention. Symptoms may include severe headache, visual disturbances, syncope, prolonged erection, or pronounced hypotension. Supportive measures should be administered; hemodialysis is not expected to significantly enhance elimination due to high protein binding.

Storage

Store below 30°C (86°F) in the original packaging to protect from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is intended for educational purposes and does not replace professional medical advice. Always consult a qualified healthcare provider for diagnosis, treatment recommendations, and personalized dosing. Do not initiate, adjust, or discontinue medication without medical supervision.

Reviews

Clinical studies and post-marketing surveillance indicate high patient satisfaction with Manforce when used as directed under medical supervision. Users frequently report improved erectile function, confidence, and overall sexual satisfaction. Individual responses may vary based on underlying health, adherence to dosing instructions, and presence of concomitant medications.