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Generic Monoket (Isosorbide mononitrate)
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Monoket
Monoket is used for treating and preventing angina.
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Donald J. When radiolabelled isosorbide mononitrate was administered to humans in order to elucidate the Mnoket fate, about half of the dose was found denitrated and renally excreted as isosorbide and sorbitol. In general, IMD is well tolerated. Eighteen studies investigated bioavailability, pharmacokinetics or clinical outcomes following manipulations which included nine delayed or modified release formulations. Company: Kremers Urban Pharmaceuticals. Trinitrina Trinitrina: Per quali malattie si usa? The volume of distribution is approximately 0. Il mal di testa scompare generalmente durante il proseguimento della terapia. This list is not complete. Get up slowly and steady yourself to prevent a fall. Are generic drugs as safe as brand-name drugs? Skip to Content. If you use too much Monoket, it might stop Monoket as well in controlling your condition. It is not known whether Monoket will harm an unborn baby. Dosage Form Tablet - A solid dosage form containing medicinal substances with or without suitable diluents. See also: Monoket side effects in more detail. The principal pharmacological action of isosorbide mononitrate is relaxation of vascular smooth muscle and consequent dilatation of peripheral arteries and veins, especially the latter. Call your doctor for medical advice about side effects. Generic Name: isosorbide mononitrate Dosage Form: tablet. This medicine may interact with several other drugs such as tricyclic antidepressants and cough medicines. Email Address. Extremely rarely, ordinary doses of organic nitrates have caused methemoglobinemia in normal-seeming patients; for further discussion of its diagnosis and treatment see Overdosage. Hypotension induced by isosorbide mononitrate may be accompanied by paradoxical bradycardia and increased angina pectoris. Dilatation of the coronary arteries also occurs. Treatment Monoket isosorbide mononitrate may Mlnoket associated with light-headedness on standing, especially just after rising from a recumbent or seated position. See also: Monoket drug interactions in more detail. The duration if any of antianginal activity beyond fourteen hours has not been studied. Come si utilizza e quando non dev'essere usato? A cosa serve? All Monokeh should include a daily dose-free interval of at least 14 hours to prevent the development of drug tolerance. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Peak plasma concentrations Momoket occur in about minutes. Laboratory determinations of serum levels of isosorbide mononitrate and its metabolites Monokket not widely available, and such Monokt have, Monokt any event, no established role in the management of isosorbide mononitrate overdose. This article reviews the Monoket and pharmacokinetics of a number of new dosage formulations e. You may also need a second dose later in the day. Steven De Bruyn. Drug Class. The pharmacological effect was determined using digital pulse plethysmography and the orthostatic tilting test, and at the same time side effects were monitored. The method was fully validated with respect to linearity, sensitivity, specificity, recovery, accuracy, and precision. This drug should therefore be used with caution in patients who may be volume depleted or who, for whatever reason, are already hypotensive. In the large majority of these trials, active agents were indistinguishable from placebo after 24 hours or less of continuous therapy. Monoket drug interactions in more detail. About About Drugs. All rights reserved. Patologie del sistema muscolo - scheletrico e del tessuto connettivo. A salient feature of drugs used in prophylaxis is a long duration of action. Medically reviewed by Drugs. Mathematical comparison of curves with an emphasis on dissolution profiles. Store at room temperature away from moisture, heat, and light. The onset of action of oral isosorbide mononitrate is not sufficiently rapid Monoket this product to be useful in aborting an acute anginal episode. In patients undergoing continuous ambulatory peritoneal dialysis, blood levels are similar to patients not on dialysis. Monoket is used to prevent angina attacks chest pain. Follow all directions on your prescription label. May repeat dose q 5 to 10 minutes for a total of three doses in 15 to 30 minutes. To avoid the development of nitrate tolerance secondary to relatively constant elevated plasma nitrate concentrations, intermittent nitrate dosing has been advocated. KeywordsColumn liquid chromatography-Tandem mass spectrometry-Pharmacokinetic study-Isosorbide dinitrate and isosorbide 5-mononitrate. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. See table at end of Pregnancy section for animal-to-human dosage comparisons. Teva Product Catalog The product catalog provides you with a full listing of Teva's brand and generic product lines. The detection was carried out by means of electrospray ionization mass spectrometry in negative ion mode with selected ion recording SIR. Alcohol may increase certain side effects of isosorbide mononitrate dizziness, drowsiness, feeling light-headed, or fainting. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This is the date when the listing record will expire if not updated or certified by the product labeler.
Common use

Monoket is used for treating and preventing angina. It can be used to decrease the frequency and severity of anginal (chest pain) episodes and to reduce the need for sublingual (under the tongue) nitroglycerin. Monoket is in a group of drugs called nitrates. It makes it easier for blood to flow through them and easier for the heart to pump. Monoket will not treat an angina attack that has already begun.



Dosage and direction

Dosage of Monoket depends on prescription of your doctor. Do not take it in larger amounts or for longer than it was recommended. Follow the directions on your prescription schedule. Your doctor may suddenly change your dose to make sure you get the best results from this medication. Not all brands and forms of Monoket are taken in the same way. Follow your doctor's dosing instructions very carefully. Take this medication with water or other liquid. Do not crush, chew, or break an extended-release tablet. The best way to take it is to swallow the pill whole. Breaking the pill may cause too much of the drug to be released at one time. It is important to keep taking this medicine as directed to prevent an angina attack.



Precautions

Try to rest or stay seated when you use this medication. Monoket can cause dizziness or fainting. Get up slowly and steady yourself to prevent a fall. Before taking isosorbide mononitrate, tell your doctor if you have congestive heart failure, low blood pressure, or kidney disease. It is important to keep taking this medicine as directed to prevent an angina attack. Get your prescription refilled before you run out of medicine completely. You should not stop taking isosorbide mononitrate suddenly. Stopping suddenly could cause a severe angina attack. Never change brands of isosorbide mononitrate without the approval of your doctor. If you experience something like congestive heart failure, low blood pressure or kidney disease, you may need a dose adjustment or special tests to safely take Monoke. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of Monoket.



Contraindications

You should not take Monoket if you have hypersensitivity to this drug (its components), hypotension, volume depletion, acute MI, CHF and hypertrophic cardiomyopathy.



Possible side effects

The most common side effect of Monoket is headache and it usually is related to increase of dose. Monoket may cause a severe drop in blood pressure when rising from a sitting position, causing dizziness, palpitations, and weakness. To reduce the risk of low blood pressure, patients should rise slowly from a sitting position. You need emergency medical help if you have any of signs of an allergic reaction (hives, difficulty breathing, swelling of your face, lips, tongue, or throat). Serious side effects include fast, slow, pounding, or uneven heart rate; feeling like you might pass out; trouble breathing, blue-colored skin, tired feeling or worsening angina pain. Less serious side effects may include headache, mild dizziness; warmth, redness, or tingling under your skin; nausea, vomiting, constipation, diarrhea; pain or stiffness in joints or muscles; hot flashes; or dry mouth.



Drug interactions

Patients taking Monoket should not receive sildenafil, tadalafil or vardenafil. Because sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) increase the blood pressure lowering effects of Monoket and may cause excessive reductions in blood pressure.

Also severe reductions in blood pressure, especially when changing posture (orthostatic hypotension), may occur when Monoket is combined with diltiazem (Cardizem, Dilacor, Tiazac and several others), verapamil (Calan, Verelan, Verelan PM, Isoptin, Isoptin SR, Covera-HS), which also reduce blood pressure. Also inform your doctor about all other medications you use: blood pressure medication; dihydroergotamine (D.H.E. 45, Migranal) or ergotamine (Ergomar, Cafergot); an erectile dysfunction medication; a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or a calcium channel blocker such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others.



Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose



Overdose

Overdose symptoms may include a severe throbbing headache, fever, confusion, dizziness or spinning sensation, fast or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cold or clammy skin, feeling light-headed, fainting, and seizure (convulsions). An overdose of Monoket can be fatal. Seek emergency medical attention if you think you have used too much of this medicine.

Storage

Store Monoket at room temperature15-30 C (59-86 F) in a tight container, away from moisture, heat, and light. Keep the bottle tightly closed when not in use.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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Asthma Treatment

Asthma is a chronic inflammatory disease of the respiratory tract. In cases of predisposition this inflammation causes recurring cough, stertor, the feeling of pressure in the chest, difficulty breathing. The inflammation makes the respiratory tract sensitive to allergens, chemical irritants, tobacco smoke, cold air and physical exercise. These irritants cause swelling and respiratory tract spasm, increased quantities of mucous are produced and the respiratory tract becomes hypersensitive to external affections. If the condition is adequately treated then the inflammation may decrease for a long period of time as well as frequency of symptom appearance decreases, concomitant symptoms of bronchial asthma may also disappear.

By severity of the disease 4 forms of asthma are distinguished:

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  • Mild remission
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  • Severe persistent

The disease most frequently proceeds in classical form as suffocation episodes followed by remission periods.

Bronchial asthma treatment depends on the period of the disease. During the acute episodes it is necessary to inhibit it as soon as possible with broncho-spasmolytic drugs, which may belong to different groups: stimulators of adrenergic receptors, theophylline, methylxanthines.

During the remission period of bronchial asthma specific immunotherapy(hyposensibilization) may be performed. A very important part of the therapy consists in exercise, rational nutrition, daily regimen which will include long periods of time in contact with fresh air.

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Nearly 300 million people were affected worldwide and about 20 million of people suffer in USA suffer from asthma. In 2009 asthma caused 250,000 deaths globally. Asthma affects people of all ages, but it most often starts during childhood. In the United States, more than 22 million people are known to have asthma. Nearly 6 million of these people are children.

Asthma is a long-term disease that can't be cured. Asthma medicines can be either inhaled, using a metered dose inhaler, dry powder inhaler, or a nebulizer, or taken orally, either in pill or liquid form. Medications can also be given by injection. An inhaler allows the medicine to go directly to your lungs where it is needed most.

What is Albuterol / Ventolin Inhaler

Due to the fact that there is no cure for asthma and other associated lung diseases, you will always find that most of the methods have been initiated to help in controlling these conditions. Generic albuterol inhaler is one of these methods that in most cases will help you in controlling your asthma conditions.Genetic albuterol inhaler is always prescribed to help you in managing the asthma conditions in your body especially exercise induced asthmas conditions. Apart from asthma, this prescription can also help you to deal with other lung associated diseases. Due to the fact that the old typesof genetic albuterol inhale were a threat to both the users and environment, you will never get them in the current market.This is because they always contain some chlorofluorocarbons which are always a threat to your health and also poses some danger to the atmosphere.

When looking for the current generic albuterol inhale, in most cases you will get them inform of Proair HFA, Proventil HFA, or Ventolin HFA. You should always make sure that you do not confuse these kinds of medicine with others sharing the same prefix. It is estimated that the next new batch or version of generic albuterol inhaler it will be in the market by 2014. It is expected that the ventolin HFA version to expire by the year 2015 by October to be more precise. If you need to get some benefit of this kind of medicine, this is the right time for you to have the medicine.

Ventolin Inhalers is the preferred medicines for long-term control of asthma. Ventolin Inhaler i.e. Albuterol is belongs to a class of medications called bronchodilators or beta-agonists (helps easier breathing by telling the muscles of the airways to relax, widening the airways). VENTOLIN HFA (albuterol sulfate inhalation aerosol) is indicated for the treatment or prevention of bronchospasm with reversible obstructive airway disease and prevention of exercise-induced bronchospasm. It works very quickly to relieve asthma attacks, wheezing, chest tightness or shortness of breath. Ventolin hfa inhalers works by relaxing the muscles in the walls of the small airways in the lungs. This helps to open up the airways and make breathing easier. They're the most effective option for long-term relief of the inflammation and swelling that makes your airways sensitive to certain inhaled substances. Albuterol (over the counter asthma drug) is also used to prevent the symptoms of exercise-induced asthma.

Care should always be taken especially when you are using generic albuterol inhale. This is because it may result to other body complications if you use the medicine wrongly. Therefore it is important to always follow the prescriptions given by your health care provider especially if good results and fast healing is your targets.

This medicine should always be used for the right purpose and by the right person. It is always good to put it always from the reach of children and a safe place when not in use. Still when you are using it, it is also good and advisable to put away from fire. This is because it may explode thus causing some other unplanned inconveniences.

Generic albuterol inhale: cost and affordability

Though the new generic albuterol inhales always much more effective on how they deal with lung related condition, you will always find them to be a bit more expensive than the old versions. This should not worry you because having them, you are always guaranteed that you will be able to deal with all lung related infections which are life-threatening conditions. The other alternative that you can always use is the various programs which are usually available in most of health facilities. There are various sources that you can always get this medicine ranging from the local pharmaceuticals to the international source but considering an online source is always good for you. This is because it is always a reliable and an easier way to purchase generic albuterol inhale. Online method is also good for you because it always saves your time and cost for the medicine.

Generic albuterol inhale dosage

When treating asthma, it usually advisable you start with one to two sprays especially for the exercises related asthmas. Before you start exercising, it is recommended that you take about two sprays about 15-30 minutes before. In most cases when there are no changes with the use of this prescription, it is always good that you seek for a health provider intervention so that you can get another kind of medication. In order to prevent some of the shortcoming associated to asthma, it is always good that you carry your generic albuterol inhale with you in order to use when there is an emergency.

How to Use a Metered Dose Inhaler / Ventolin Inhaler

In most cases when using generic albuterol inhale, it is always advisable that you spry about once or twice especially before you start your exercises. This helps in preventing asthma that is induced by exercises related activities. It is usually recommended that you do it about 15-30 minutes before the actual time for your exercises. If the condition arises during the exercises and it happens that it is worse than usual, you are supposed to seek for a physician help since it may put your life at risk.

When starting your generic albuterol inhale medication, in most cases you will find that your health provider has to consider some factors before prescribing you with any medicine of this kind. One of the condition is what you are intending to do with the medicine. Is it preventing or treating asthma? He or she also considers whether you have other diseases affecting you and if there are no diseases, what is your asthmatic severity. This helps you in getting the proper dose that will work on your condition in the right way without altering your body functionality.Apart from this consideration, it is always important to always inform your physician about other medicine that you are also taking before you begin using generic albuterol inhale. This help in knowing the amount you are supposed to take. It also important for interaction purposes due to the fact that other medications may affect how your new medicine works in your body asthmatic condition.

After you receive your asthma prescriptions, it is always good to remember to carry it with you to wherever you are going. This is because the condition may arise at any point especially when you are not prepared for it. This can be serious especially if the asthma is allergic to atmospheric changes. In cases when you do not see any changes with the use of generic albuterol on your health, it is always important to seek for a medical intervention immediately. This is because the condition may put your life at risk especially if it is the first time to be affected by the asthma.

How you intend to use the medicine as mentioned earlier is important. This is because some people always use generic albuterol for preventing asthma attack while others use it to manage the condition. It is therefore important to always test the medication before you start using it. This helps you to be aware that the prescription is really working in order to prevent some inconveniences when the condition arises.When inhaling, it is important you always shake the medicine well and also to wait for about a minute before you use it. Learning these simple but important tips for using your generic albuterol inhale helps in avoiding difficulties and other shorting comings that accompany the use of this medicine.

Remember also that this medicine should always be used in your lungs but not just spraying at the back of your throat as many do. You should also not swallow the medicine. In order to avoid all these short comings, it is always advisable when using it to always breathe in. apart from this technique, most health care professionals always tells people with this condition to always place the inhale about one to two inches always from their mouth. This helps you in preventing direct swallowing the medicine. For more information on how to use generic albuterol inhale, you should always make sure that you contact your health provider for more directions.

In most cases your generic albuterol inhale contains about 200 sprays. It is always good to track how you are using it in order to replace it when need arises. Unlikethe older versions of this medicine which was hard to track their uses, the new version especially the Ventolin HFA has an automatic counter that help you in put track of your medicine use. In most cases, it is always good to be around other people so that in case of emergency you can always get help from them. If you have problems in using your generic albuterol inhale in the right ways, a professional interventions is always recommended for you.