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Combivent is prescribed to treat chronic obstructive pulmonary disease. The medication works by dilating and enlarging the airways via relaxation of the muscles of respiratory tract.
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50/20mcg
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50/20mcg
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50/20mcg
6inhalers |
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$187.19
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Delivery period 14-21 days |
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The principle of action of Combivent inhalations
Combivent contains two active components, each of which can relieve bronchial spasm, stimulate the production and discharge of sputum. The drug belongs to the group of M-cholinoblockers and β-2 adrenomimetics.
The basis of the drug is Ipratropium bromide, which has a pronounced anticholinergic property, which allows it to relieve bronchospasm during inhalation, improve the function of the lungs and bronchi. Salbutamol is the second component of the drug, the mechanism of action of which is aimed at relaxing the smooth muscles of the bronchi, which allows you to stop the development of bronchospasm. This substance has the ability to block mediators of inflammation and allergies from mast cells. Combivent consists of Salbutamol, which has the ability to have a stimulating effect on the β-2 adrenoreceptors of the heart and blood vessels, thereby increasing the heart rate.
Using Combivent inhalations through a nebulizer, you can increase the effect on the muscles of the bronchi, accelerate the removal of sputum, and achieve a rapid therapeutic effect in various diseases of the respiratory system with the obstruction.
Combivent for bronchial obstruction
Ipratropium bromide has a bronchodilating effect, blocks some receptors in the tissues of the bronchi, which allows you to relax smooth muscles, reduce the secretion of mucus production. The advantage of the drug is its local action. Using the drug, you can not only quickly remove the spasm of the bronchi but also remove accumulated mucus from the respiratory system, thereby quickly stop an asthmatic attack, restore breathing. The speed of the drug action depends on the severity of the disease, but mainly the effect of inhalation with Combivent appears from 5 to 10 minutes and persists for 6 hours.
Indications for use
Instructions for the use of Combivent informs that the drug is intended for children and adults with a history of obstructive diseases of the bronchi and lungs. The drug can be used both in the acute period of the disease, when there is bronchospasm and for the treatment of dry cough with difficult to separate sputum, which often causes the child to vomit. The main indications for the use of Combivent are the following diseases and conditions:
Emphysematous bronchitis.
Bronchial asthma in the acute period.
Emphysema.
The bronchospasm and pneumonia.
Obstructive syndrome of the bronchi and lungs.
Inhalation with this drug is widely used for bronchitis, laryngitis, when there is a strong and painful unproductive cough. Using inhalation procedures, it is possible to deliver the drug directly to the focus of inflammation, which provides the fastest possible therapeutic effect in attacks of suffocation, which are caused by a spasm of the bronchi. The instructions contain information that the drug can be used for chronic respiratory diseases, which significantly reduces the risk and number of exacerbations.
Side effects of Combivent inhalation
Inhalation with Combivent is perfectly tolerated by adults and children, but in some cases, the following ailments may appear after the procedure:
Dry mouth.
Changing taste preferences.
Headache.
Heart rhythm disorder.
Violation of the respiratory system – cough.
Paradoxical bronchospasm.
The appearance of the above symptoms may cause the drug to be discontinued. If you want to reduce the risk of adverse reactions, you need to strictly follow the recommended doses of the drug, and also have information about the period when you can do inhalation to eliminate the risk of overdose.
Common use
Combivent contains two active substances: ipratropium bromide (Atrovent) and Levosalbutamol. Ipratropium blocks m-cholinoreceptors of smooth muscles in the bronchi and treacheas, suppresses reflect constriction of bronchis, decreases secretion of the mucous membrane in the respiratory tract. The drug is used in treatment of chronic obstructive pulmonary disease with spasm of the airways. Effect of bronchodilators consists in dilatation and enlargement of the airways by relaxing the muscles of respiratory tract. Ipatropium works different way, it has a structural similarity with acetylcholine and becomes its competitive antagonist. The medication effectively prevents spasm of the bronchi due to breathing with cigarette smoke, cold air, activity of different agents which cause spasm of bronchi associated with influence of n.vagus.
Dosage and direction
Each condition and patient need individual dose.
Precautions
Cautiousness should be exercised in individuals with close-angle glaucoma, urinary tract obstruction (prostatic hypertrophy), problems with urination;, coronary artery disease, hypertension, heart failure, tachyarrhythmia, epileptic syndrome, hyperthyroidism, diabetes mellitus, hypokalemia, liver or kidney failure, pregnancy, breastfeeding women. Safety of Combivent has not be studied in children.
heart disease, high blood pressure, or congestive heart failure;
Contraindications
The medication cannot be used in patients with known hypersensitivity to the components of Combivent, atropine (Atreza, Sal-Tropine), peanuts, soybeans, or other food products that contain soya lecithin.
Possible side effect
If signs of allergic reaction become bothersome you should immediately contact your doctor or pharmacist. Other most frequent adverse reactions include bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new inhaler, uneven heart beats, chest pain and fast, pounding, increased blood pressure (severe headache, chest pain, numbness, seizure, blurred vision, trouble concentrating), swelling of your ankles or feet, pain or burning with urination,.
Drug interaction
Inform your doctor about all medications and herbal products you are taking and especially about atropine (Donnatal, and others), belladonna preparations, clidinium (Quarzan), mepenzolate (Cantil), glycopyrrolate (Robinul), methantheline (Provocholine), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), dicyclomine (Bentyl), propantheline (Pro-Banthine), propantheline (Pro-Banthine), methscopolamine (Pamine), scopolamine (Transderm-Scop), methscopolamine (Pamine), scopolamine (Transderm-Scop), a beta-blocker such as carvedilol (Coreg), atenolol (Tenormin, Tenoretic), metoprolol (Lopressor), propranolol (Inderal); methscopolamine (Pamine), scopolamine (Transderm-Scop), diuretics, diet pills, a stimulant, ADHD medication, or over-the-counter cold or allergy medicines, an MAO inhibitor such as phenelzine (Nardil), isocarboxazid (Marplan), rasagiline (Azilect), selegiline (Eldepryl, Emsam),or tranylcypromine (Parnate).
Missed dose
Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.
Overdose
Combivent overdose may be fatal. If you experience rapid or uneven heart rate, chest pain or heavy feeling, weakness, pain spreading to the arm or shoulder, nausea, sweating, or general ill feeling contact your pharmacist or doctor immediately.
Storage
Combivent inhaler should be stored at room temperature between 15-30 C (59-86 F).
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.