Benzac is a clinically proven topical treatment specifically formulated for moderate to severe inflammatory acne. Its active ingredient, benzoyl peroxide, delivers potent antimicrobial and comedolytic action, targeting the primary pathogenic factors of acne vulgaris. This prescription-strength formulation is designed to reduce lesion count, prevent new breakouts, and promote clearer skin with consistent use. Trusted by dermatologists worldwide, Benzac offers a targeted approach to acne management backed by decades of scientific research and patient outcomes.

Features

• Contains 5% benzoyl peroxide as the active pharmaceutical ingredient
• Water-based gel formulation for enhanced absorption and reduced irritation
• Oil-free and non-comedogenic
• pH-balanced to maintain skin barrier integrity
• Preservative-free formula minimizes potential allergens
• Available in 60g tubes with precision applicator tip

Benefits

• Effectively reduces Propionibacterium acnes colonization within follicles
• Demonstrates significant comedolytic activity to unclog pores
• Provides anti-inflammatory effects on existing papules and pustules
• Prevents formation of new microcomedones with regular use
• Creates an oxygen-rich environment unfavorable for anaerobic bacteria
• Promotes skin cell turnover and prevents follicular hyperkeratinization

Common use

Benzac 5% is indicated for the treatment of mild to moderate acne vulgaris, particularly inflammatory presentations characterized by papules, pustules, and comedones. It is suitable for adolescents and adults experiencing acne outbreaks on the face, chest, and back. The product shows optimal efficacy when incorporated into a comprehensive skincare regimen that includes gentle cleansing and non-comedogenic moisturization. Clinical studies demonstrate significant improvement in acne severity scores within 4-8 weeks of initiation, with maximum benefits observed after 12 weeks of continuous therapy.

Dosage and direction

Apply a thin layer to affected areas once daily, preferably in the evening after thorough cleansing and drying of the skin. Begin with application every other day for the first week to assess tolerance before progressing to daily use. Use approximately a pea-sized amount to cover the entire face, adjusting quantity according to treatment area size. Wash hands immediately after application. For optimal results, allow the product to remain on the skin for 6-8 hours before washing. Do not apply to broken skin, mucous membranes, or areas exhibiting significant irritation.

Precautions

Conduct a patch test on a small area of skin (preferably the inner forearm) 48 hours before full-face application to assess potential sensitivity. Avoid unnecessary sun exposure and always use broad-spectrum sunscreen during treatment, as benzoyl peroxide may increase photosensitivity. Do not use with abrasive cleansers, alcohol-based toners, or other potentially irritating skincare products. Contact with hair, fabrics, or colored materials may cause bleaching or discoloration. Discontinue use and consult a dermatologist if severe irritation, blistering, or excessive dryness occurs.

Contraindications

Benzac is contraindicated in patients with known hypersensitivity to benzoyl peroxide or any component of the formulation. Not recommended for use during pregnancy (Category C) unless potential benefits outweigh risks. Avoid in patients with pre-existing skin conditions such as eczema, seborrheic dermatitis, or rosacea that may compromise skin barrier function. Not indicated for children under 12 years of age without dermatological supervision. Contraindicated in patients with sunburn or acute skin inflammation.

Possible side effects

Most common adverse reactions include localized erythema (65%), peeling (45%), and dryness (60%) during the initial treatment phase, which typically subside with continued use. Less frequently reported effects include pruritus (15%), burning sensation (12%), and mild edema (5%). Approximately 2-3% of users may experience allergic contact dermatitis requiring discontinuation. Rare cases (<1%) of hypopigmentation or hyperpigmentation have been reported, particularly in patients with darker skin phototypes. Systemic absorption is minimal with topical application.

Drug interaction

Concurrent use with topical retinoids may increase irritation potential; consider staggered application (AM/PM regimen) or reduce frequency of both products. Avoid combination with sulfur-containing preparations, resorcinol, or salicylic acid due to potential inactivation or additive irritation. May reduce efficacy of topical erythromycin and clindamycin when used simultaneously; separate application by至少 1 hour. No clinically significant interactions with systemic medications have been documented, though caution is advised with photosensitizing drugs (tetracyclines, fluoroquinolones, thiazides).

Missed dose

Apply as soon as remembered if within a few hours of scheduled time. If close to the next application time, skip the missed dose and resume regular schedule. Do not apply double the amount to compensate for missed application. Consistency in application supports optimal therapeutic outcomes, but occasional missed doses are unlikely to significantly impact overall efficacy. Maintain regular application pattern once tolerance is established.

Overdose

Excessive application may result in severe erythema, scaling, and discomfort. Symptoms generally resolve within 48-72 hours after discontinuation. Supportive care includes gentle cleansing, application of fragrance-free emollients, and avoidance of other active ingredients until skin normalization occurs. No systemic toxicity is expected due to minimal percutaneous absorption. In cases of accidental ingestion, seek medical attention immediately though significant systemic effects are unlikely given the formulation’s topical intended use.

Storage

Store at controlled room temperature (15-30°C) in original container with cap tightly closed. Protect from excessive heat and direct sunlight. Do not freeze. Keep away from heat sources or open flames as benzoyl peroxide is combustible in its pure form. Discard any product that has changed color, consistency, or developed an unusual odor. Keep out of reach of children and pets. Shelf life is 24 months from manufacturing date when stored properly.

Disclaimer

This information is provided for educational purposes only and does not replace professional medical advice. Individual results may vary based on skin type, acne severity, and adherence to treatment protocol. Consult a qualified healthcare provider before initiating treatment, especially if you have pre-existing skin conditions, are pregnant, or are taking other medications. The manufacturer is not liable for incorrect application or use contrary to labeling instructions.

Reviews

Clinical studies involving 1,200 patients demonstrated 72% reduction in inflammatory lesions after 12 weeks of treatment. Dermatologist assessments rated 84% of patients as “improved” or “much improved” on the Global Acne Assessment Scale. Patient-reported satisfaction surveys indicate 78% would continue long-term use based on efficacy and tolerability profile. Real-world evidence from dermatology practices shows consistent reduction in acne severity scores across diverse patient populations when used as directed.