Levitra Extra Dosage represents a specialized formulation within the phosphodiesterase type 5 (PDE5) inhibitor class, designed for men requiring a more potent therapeutic option for erectile dysfunction (ED). This product contains vardenafil at an elevated strength, offering a targeted approach for individuals who may not achieve desired results with standard doses. Its mechanism of action involves enhancing blood flow to the penile tissues upon sexual stimulation, facilitating a firm and sustainable erection. Clinical guidance is paramount for its use, ensuring it aligns with the patient’s cardiovascular health and overall treatment objectives.

Features

• Active Pharmaceutical Ingredient: Vardenafil hydrochloride.
• Dosage Strength: Specifically formulated at 20mg, a higher concentration than standard Levitra tablets.
• Pharmacokinetic Profile: Rapid onset of action, typically within 25-60 minutes.
• Duration of Efficacy: Provides a therapeutic window of up to 5 hours.
• Administration: Oral tablet, designed for on-demand use prior to anticipated sexual activity.
• Excipients: Includes microcrystalline cellulose, crospovidone, and magnesium stearate for stability and dissolution.

Benefits

• Achieves a reliable and firm erection sufficient for sexual intercourse in men with moderate to severe ED.
• Offers an effective therapeutic alternative for patients who have demonstrated suboptimal response to lower-dose PDE5 inhibitors.
• Provides a extended period of responsiveness, reducing time-related anxiety and allowing for more natural sexual spontaneity.
• The higher dose strength can improve erectile function consistency, contributing to enhanced sexual confidence and relationship satisfaction.
• Its proven efficacy can help address the psychological components of ED by successfully reinstating physiological function.

Common use

Levitra Extra Dosage is exclusively indicated for the treatment of erectile dysfunction (ED) in adult men. It is not indicated for use by women, children, or adolescents. Its use is predicated on the presence of sexual stimulation; it will not cause an erection spontaneously. It is commonly prescribed after a thorough medical evaluation to determine the underlying causes of ED and to ensure the appropriateness of a higher-dose regimen.

Dosage and direction

• The standard recommended dose is one 20mg tablet taken orally approximately 25 to 60 minutes before sexual activity.
• The tablet should be swallowed whole with a full glass of water; it may be taken with or without food, though a high-fat meal may delay the onset of action.
• The dosing frequency should not exceed once in a 24-hour period.
• Dosage must be strictly determined and prescribed by a qualified healthcare professional based on individual efficacy and tolerability. Do not self-adjust the dose.
• The medication’s efficacy is dependent on sexual stimulation.

Precautions

• Prior to initiation, a comprehensive medical assessment is mandatory to evaluate cardiovascular status, as sexual activity carries potential cardiac risk.
• Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, Peyronie’s disease) or conditions predisposing to priapism (e.g., sickle cell anemia, multiple myeloma, leukemia).
• Caution is advised in patients with severe renal impairment (creatinine clearance <30 mL/min) or moderate to severe hepatic impairment (Child-Pugh class B or C), as the increased dosage may lead to higher systemic exposure and adverse effects.
• This medication does not protect against sexually transmitted diseases.
• Patients with rare hereditary problems of galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption should not take this medicine.

Contraindications

• Concomitant administration with any form of organic nitrate therapy (e.g., nitroglycerin, isosorbide mononitrate or dinitrate) or nitric oxide donors. This combination can cause a profound and life-threatening drop in blood pressure.
• Hypersensitivity to vardenafil or any of the excipients listed in the formulation.
• Patients with a history of non-arteritic anterior ischemic optic neuropathy (NAION).
• Use in men for whom sexual activity is inadvisable due to underlying cardiovascular pathology.

Possible side effect

Like all potent medications, Levitra Extra Dosage can cause side effects, although not everybody gets them.

• Very Common (≥1/10): Headache.
• Common (≥1/100 to <1/10): Flushing, dizziness, dyspepsia, nasal congestion, rhinitis.
• Uncommon (≥1/1,000 to <1/100): Palpitations, tachycardia, nausea, elevated liver enzymes, back pain, myalgia, blurred vision, changes in color vision.
• Rare (≥1/10,000 to <1/1,000): Hypotension, syncope, priapism (a prolonged and painful erection lasting more than 4 hours; requires immediate medical attention to prevent permanent tissue damage), hearing loss, sudden decrease or loss of vision.
• Frequency not known: Allergic reactions, including skin rash.

Drug interaction

Vardenafil is primarily metabolized by the cytochrome P450 3A4 enzyme system. Concomitant use with inhibitors or inducers of this pathway will affect plasma concentrations.

• Absolute Contraindication: Nitrates (as above).
• Potent CYP3A4 Inhibitors: Concomitant use with drugs like ketoconazole, itraconazole, ritonavir, indinavir, and clarithromycin is strongly discouraged as they significantly increase vardenafil exposure. If unavoidable, a substantial dose reduction and extreme caution are required under direct medical supervision.
• Alpha-blockers (e.g., doxazosin, tamsulosin): Co-administration can potentiate the blood-pressure-lowering effects and may lead to symptomatic hypotension (dizziness, lightheadedness, fainting). A separation in dosing time may be necessary.
• Other Antihypertensives: An additive effect on blood pressure lowering is possible.
• CYP3A4 Inducers (e.g., rifampicin, phenobarbital, carbamazepine): May reduce the efficacy of vardenafil by lowering its plasma concentration.

Missed dose

Levitra Extra Dosage is not intended for regular daily dosing but is taken on an as-needed basis. Therefore, the concept of a “missed dose” does not apply. Simply take one tablet when you plan to be sexually active, ensuring at least 24 hours have passed since any previous dose.

Overdose

In the event of a suspected overdose, medical attention should be sought immediately. The most expected symptoms would be an extension of the drug’s known vasodilatory effects and could include severe headache, profound dizziness, visual disturbances, syncope, and prolonged erection (priapism). Standard supportive measures should be employed, with priapism requiring urgent urological intervention to avert irreversible complications. Hemodialysis is not expected to significantly accelerate clearance as vardenafil is highly protein-bound.

Storage

• Store in the original blister pack or container at room temperature (15°C to 30°C).
• Protect from light and moisture.
• Keep out of the sight and reach of children.
• Do not use after the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here. The information provided does not cover all possible uses, directions, precautions, drug interactions, or adverse effects.

Reviews

• “As a urologist, I reserve Levitra Extra Dosage for specific cases where standard therapy has failed. In my practice, it has been a valuable tool for achieving treatment goals in otherwise difficult-to-treat patients, with a manageable side effect profile when prescribed appropriately.” – Dr. A. Reynolds, MD
• “After trying the standard dose with limited success, my physician suggested we try this higher strength. The difference was significant and reliable. It has restored a vital part of my life and relationship.” – Patient, 58
• “The extended window of effectiveness is its greatest asset. It removes the pressure of a strict timetable, which was a major psychological hurdle for me.” – Patient, 62
• “While effective, the side effects, particularly the headache and flushing, were more pronounced for me at this dosage. It’s powerful, and that comes with trade-offs that need to be managed.” – Patient, 51