Bactroban Ointment 5g: Targeted Topical Antibiotic Treatment
| Product dosage: 20mg | |||
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| 10 | $20.02
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Synonyms | |||
Bactroban Ointment 5g contains mupirocin 2% w/w as the active ingredient, formulated specifically for topical application to treat localized bacterial skin infections. This prescription medication is indicated for primary impetigo and secondary infected traumatic skin lesions caused by susceptible strains of Staphylococcus aureus and Streptococcus pyogenes. Its unique mechanism of action inhibits bacterial protein synthesis, providing effective eradication of pathogens at the infection site with minimal systemic absorption when applied correctly under medical supervision.
Features
- Contains 2% mupirocin calcium in a water-soluble polyethylene glycol base
- 5g tube size for convenient course-of-treatment dosing
- White to off-white ointment consistency for easy application
- Bactericidal activity against gram-positive bacteria
- Minimal systemic absorption when applied topically
- Stable at room temperature storage conditions
Benefits
- Rapidly eliminates causative bacteria at the infection site
- Reduces risk of infection spreading to surrounding tissues
- Helps prevent development of more serious systemic infections
- Minimizes scarring by controlling infection progression early
- Convenient topical application avoids gastrointestinal side effects
- Short treatment course typically required (usually 5-10 days)
Common use
Bactroban Ointment is primarily prescribed for the treatment of impetigo, a contagious bacterial skin infection characterized by honey-colored crusted lesions, most commonly affecting children. It is also used for secondary infected skin lesions including small wounds, lacerations, and abrasions that have become bacterially contaminated. The ointment is particularly effective against methicillin-sensitive Staphylococcus aureus (MSSA) and beta-hemolytic streptococci. Dermatologists may also prescribe it for minor surgical site infections and as part of decolonization protocols for patients with recurrent staphylococcal infections.
Dosage and direction
Apply a small amount of ointment to the affected area three times daily for 5 to 10 days as directed by a healthcare professional. The area may be covered with a gauze dressing if desired. Wash hands before and after application unless hands are the treated area. For impetigo, gently remove any crusted material before application to ensure optimal medication contact with infected tissue. The typical amount for an adult is approximately a half-inch ribbon of ointment per 100 cm² of affected skin, adjusted proportionally for smaller areas. Do not exceed the prescribed duration unless specifically instructed by your physician.
Precautions
Use only on skin surfaces; avoid contact with eyes, nostrils, mouth, or other mucous membranes. Discontinue use and consult your physician if significant irritation, rash, or allergic reaction develops. Not for ophthalmic, intranasal, or intravaginal use. Use with caution in patients with moderate to severe renal impairment due to potential systemic absorption of polyethylene glycol base. Avoid use on large open wounds or extensive burn areas without medical supervision. Pregnancy Category B: use only if clearly needed after risk-benefit assessment. Exercise caution when breastfeeding as unknown whether mupirocin is excreted in human milk.
Contraindications
Hypersensitivity to mupirocin or any component of the formulation. Contraindicated in patients with known hypersensitivity to polyethylene glycol. Should not be used for the treatment of deep abscesses, carbuncles, or other closed-space infections that require surgical drainage and systemic antibiotics. Not indicated for the treatment of fungal, viral, or parasitic infections. Avoid use on severe burns exceeding 20% of body surface area due to potential polyethylene glycol toxicity from systemic absorption.
Possible side effects
Most common side effects include application site reactions such as burning, stinging, or pain (≤1.5%), itching (≤1.3%), and rash (≤1.1%). Less frequently reported effects include nausea (<1%), dry skin, erythema, and contact dermatitis. Rare cases of systemic allergic reactions including angioedema and anaphylaxis have been reported. Superinfection with nonsusceptible organisms including fungi may occur with prolonged use. Systemic absorption may rarely cause nausea, headache, or dizziness, particularly when applied to large surface areas or compromised skin barriers.
Drug interaction
No specific drug interactions have been clinically established with topical mupirocin. However, concurrent use with other topical products may alter absorption characteristics or cause physical incompatibility. Avoid applying other topical medications, cosmetics, or other skin products to the same area unless directed by a healthcare provider. The polyethylene glycol base may theoretically interact with other topically applied drugs by altering their absorption profile. No known interactions with systemic medications when used topically as directed.
Missed dose
Apply the missed dose as soon as remembered, unless it is almost time for the next scheduled application. Do not double the dose to make up for a missed application. Maintain the regular three-times-daily schedule, spacing applications as evenly as possible throughout waking hours. If uncertainty exists about timing, consult your pharmacist or healthcare provider for guidance. Consistent application maintains effective antibiotic concentrations at the infection site.
Overdose
Topical overdose is unlikely to cause systemic effects due to minimal absorption. However, excessive application to large body surface areas, particularly on broken skin or burns, may lead to systemic absorption of polyethylene glycol, potentially causing renal toxicity. Symptoms may include nausea, vomiting, diarrhea, metabolic acidosis, and renal impairment. In case of accidental ingestion, seek medical attention immediately as polyethylene glycol toxicity may occur. Treatment is supportive and symptomatic with attention to renal function monitoring.
Storage
Store at room temperature between 15-30°C (59-86°F). Do not freeze. Keep tube tightly closed when not in use. Protect from excessive heat and direct sunlight. Keep out of reach of children and pets. Discard any unused medication after completing the prescribed course of treatment. Do not transfer ointment to other containers as this may compromise sterility and stability. Check expiration date before use; do not use if expired.
Disclaimer
This information is provided for educational purposes only and does not constitute medical advice. Bactroban Ointment is a prescription medication requiring proper medical evaluation and supervision. Always follow the specific instructions provided by your healthcare provider and the official product labeling. Individual results may vary based on infection severity, bacterial susceptibility, and patient-specific factors. Not all possible uses, precautions, side effects, or interactions are listed here. Consult with a qualified healthcare professional for diagnosis and appropriate treatment recommendations.
Reviews
Clinical studies demonstrate Bactroban Ointment achieves clinical success rates of 85-95% in impetigo patients when used as directed. Dermatologists consistently report high satisfaction with its efficacy against susceptible gram-positive organisms. Patients appreciate the convenient dosing schedule and minimal side effect profile compared to systemic antibiotics. Some reviews note that early initiation of treatment yields best results, while delayed treatment may require longer courses or additional interventions. Healthcare providers emphasize the importance of completing the full prescribed course even if symptoms improve earlier to prevent recurrence and resistance development.